Gene: PPP1R15B ENSG00000158615

Description

protein phosphatase 1 regulatory subunit 15B [Source:HGNC Symbol;Acc:HGNC:14951]

Gene Synonyms

FLJ14744

Location

Chromosome 1: 204,396,492-204,411,887 reverse strand.

GRCh38:CM000663.2

About this gene

This gene has 5 transcripts (splice variants), 184 orthologues, 1 paralogue and is associated with 3 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq Match	Flags
ENST00000367188.5	PPP1R15B-201	5259	713aa	ENSP00000356156.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS1445	Q5SWA1	NM_032833.5	The Matched Annotation from NCBI and EMBL-EBI is a collaboration between Ensembl/GENCODE and RefSeq. The MANE Select is a default transcript per human gene that is representative of biology, well-supported, expressed and highly-conserved. This transcript set matches GRCh38 and is 100% identical between RefSeq and Ensembl/GENCODE for 5' UTR, CDS, splicing and 3'UTR.MANE Select, A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENST00000693720.1	PPP1R15B-205	2897	670aa	ENSP00000508814.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A0A8I5KSH1	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic,
ENST00000689921.1	PPP1R15B-203	4798	451aa	ENSP00000510434.1	Nonsense mediated decay		A0A8I5KUJ3	-	-
ENST00000690849.1	PPP1R15B-204	4497	453aa	ENSP00000509193.1	Nonsense mediated decay		A0A8I5KV52	-	-
ENST00000687263.1	PPP1R15B-202	4006	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	-

Gene: PPP1R15B ENSG00000158615

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Gene: PPP1R15B ENSG00000158615

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