Human (GRCh38.p14)
Description

DNA topoisomerase I [Source:HGNC Symbol;Acc:HGNC:11986]

Location

Chromosome 20: 41,028,822-41,124,487 forward strand.

GRCh38:CM000682.2

About this gene

This gene has 6 transcripts (splice variants), 270 orthologues, 1 paralogue and is associated with 61 phenotypes.

Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeq MatchFlags
ENST00000361337.3TOP1-2013734765aaENSP00000354522.2
 
Protein coding
CCDS13312P11387 NM_003286.4MANE SelectEnsembl CanonicalGENCODE basicAPPRIS P1TSL:1
ENST00000680945.1TOP1-2022532296aaENSP00000504935.1
 
Protein coding
A0A7P0T852 -GENCODE basic
ENST00000681113.1TOP1-2043938204aaENSP00000505788.1
 
Nonsense mediated decay
A0A7P0T9R7 --
ENST00000681058.1TOP1-2038092No protein-
 
Retained intron
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ENST00000681392.1TOP1-2054782No protein-
 
Retained intron
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ENST00000681884.1TOP1-2064736No protein-
 
Retained intron
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